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McGuire Family
Submitted by Diane Hitchcock-Owens
The Maguires came from Fermanagh, Ulster, Northern Ireland, where they were in hiding in Dublin from the British authorities. They were the ruling family in co. Fermanagh and had opposed vigorously, British domination. John McGuire (1) is thought to have been a "king" or chieftain from Ulster in Northern Ireland. His ancestors had fled their homes during the Flight of the Earls or the Flight of the Wild Geese with the O'Neils, O'Donnels, and O'Connels after wrongfully being charged with treason by the English crown. The family of Col. John (2) McGuire of Clark County, Kentucky, descends from James McGuire, son of John McGuire (1), who was born in 1620 in Ulster, Ireland. James married Cecilia McNamana. They had two sons: Constantine (b. 1661) and John (3) Sigismund (b. 1662). John (3) Sigismund McGuire, became a man of considerable distinction. He entered the Austrian army, as many of his kinsmen had done. He was Colonel of the McGuire Regiment, a Count of the Holy Roman Empire and Lieutenant General. He was second in command at the capture of Dresden in 1759 and as Military Governor of that city successfully resisted an attempt upon it by Frederick the Great in 1760. His elder brother, Constantine married Julia McEligot and had two sons John (4) and Edward.

Col. John (2) McGuire's was the son of Edward (1) McGuire who was born at Ardfert near Tralee about 1717. In 1746 he left Ireland. Edward McGuire came down with yellow fever which lasted for several weeks. He was left him so weakened that he thought himself unfit for a military career. He sailed directly to America and landed in Philadelphia where he disposed of his cargo and then went by way of Alexandria to the valley of Virginia.

On October 3, 1747, Edward (1) purchased from Lord Fairfax the Proprietor, a grant of 346 acres on the Wappacomo. He obtained another grant of land in Winchester, Virginia, on May 30, 1753. Land grant records show Edward (1) McGuire owned a total of more than 6,000 acres before 1760.

Edward (1) McGuire became a wealthy and influential man in Virginia. He gave the ground, as well as contributing largely to the first Catholic Church in Winchester, Virginia.

Major Edward (1) McGuire married first Susannah Wheeler of Prince George's County, Maryland. Their children were John, Anne, Elizabeth, William and Edward (2).

Major Edward's second marriage was to Milicent Dobie, daughter of Samuel Dobie. They had three children. Edward died in 1806 in Winchester, Frederick County, Kentucky.

Among his descendants is Dr. Hunter Holmes McGuire, a great grandson through Edward's son, Edward (2). Dr. McGuire was physician to Stonewall Jackson

Col. John (2) McGuire, son of Edward McGuire (1) and Susannah Wheeler, was born circa 1752. He was a chain carrier for George Washington when the latter was surveying for the Fairfax people. He served in the Revolutionary war, holding the rank of Captain. He went with George Washington, as a captain of a Virginia Company, to Cambridge, Massachusetts. He volunteered to go with Benedict Arnold in the siege or attack on Quebec. John (2)McGuire was in Grayson's regiment where he was taken prisoner in Quebec. He was later paroled, and returned to the Continental Line. He was so severely wounded at Germantown that he resigned his commission. After his service John (2) was promoted to Major and then Lt. Colonel and from that time on was known as Colonel John (2) McGuire.

Col. John (2) McGuire was a well known Indian fighter and was with George Rogers Clark at Vincennes. He returned to his home in Winchester, Virginia, before setting off for Kentucky where he settled in Clark County. There was a contingency of people who left Winchester, Virginia, for Clark County, Kentucky. The county seat, Winchester, Kentucky, is name after the Virginia town. Col. John (2) McGuire was among several notable frontiersmen and settlers of Clark County, among them were Daniel Boone, John Holder, Richard Callawway. These men's families married into the McGuire family.

Col. John (2) McGuire's home was near Ft. Boonesboro. It was located near what is now Hall's Ferry. It was previously called Combs Ferry. A restaurant now stands where the Hall Tavern once existed. This ferry was owned at the time by John Holder, husband of John's second wife.

Col. John (2) McGuire's first wife's name is not known. They had had five children. His second wife was married Frances Calloway, widow of Col. John Holder. They were married in 1802.

Frances Calloway had been captured by indians in a raid in 1776. She was rescued by John Holder. They later married and had children. He (Captain Holder) died in debt. His children were put under guardianship to various relatives. His widow, Frances, remarried Col. John (2) McGuire.

John and Frances had a daughter in 1803, Elizabeth (Betty) McGuire. Frances died in November, 1803. Col. McGuire then took his infant daughter to Tennessee to be raised presumably by relatives.

The Holder and Calloway families had moved to Tennessee. Calloway County, Kentucky, which borders the state of Tennessee, is named for Frances' father, Col. Richard Calloway.

Edward (3) McGuire, eldest son of Col. John (2) McGuire was a soldier in the War of 1812. He married Frances W. Holder, daughter of John Holder and Frances Calloway. He moved to Cape Girardeau, Missouri, where he died. His widow died at Aberdeen, Mississippi, at an advanced age.

Edward (3) McGuire, eldest son of Col. John (1) McGuire was a soldier in the War of 1812. He married Frances W. Holder, daughter of John Holder and Frances Calloway. He moved to Cape Girardeau, Missouri, where he died. His widow died at Aberdeen, Mississippi, at an advanced age.

John (2) McGuire's cousin was James McGuire who was killed at Blue Licks Battle in 1782.

William McGuire, son of Col. John (2) Mcguire and his first wife, was born on April 29, 1799, in Clark County, Kentucky. In 1806 he married Susannah Daniel, daughter of Beverly Daniel and Mary Mickelborough, in Clark County, Kentucky. Their land was located the Indian Old Field on Lulbegrub.

During the War of 1812 he served as a lieutenant in a Kentucky company, and after his return home was elected to the Kentucky Legislature.

About 1820 William and Susannah and their family went to Missouri where they settled in Jackson, Cape Giradeau. There he conducted a tanyard. He was an intelligent and popular gentleman, and served one term in the Missouri Legislature.

William and Susannah had a family of four sons and seven daughters. He died on July 20, 1857.

The following is from History of Southeast Missouri, (page 780, Goodspeed, 1888):
His family consisted of four sons and seven daughters. They were JOHN WILLIS (who married a daughter of JOHNSON RANNEY); JAMES M. (who married successively LUCINDA FARRAR, MARTHA FARRAR, and RACHEL FERGUSON); WILLIAM E. (who married ELIZABETH FARRAR); ELIZABETH (Mrs. GREER W. DAVIS); SUSAN (Mrs. ADLAI BREVARD); BERNARD S. (who married MARY DE LASHMUTT); EMILY (Mrs. ROBERT BROWN); MARY M; LUCRETIA (Mrs. DR. WILLIAM WEST); SARAH A.(Mrs. DR. D. T. PACE); and AMANDA (Mrs. J. D. MCFARLAND). ...At the breaking out of the Civil War the four MCGUIRE brothers--JOHN WILLIS, JAMES MADISON, WILLIAM E. and BERNARD S.--were opposed to secession, while those of their sons who were old enough sympathized with the South and joined her armies. WILLIAM E. MCGUIRE expressed his disapproval of the South's course by taking an ax and publicly chopping down in the presence of a town full of rebel volunteers the first Confederate flag-pole they raised. But when what was known as the Iron Clad Oath was proposed to him he refused to take it, and rather than go to prison he decided to follow the fortunes of the South, and went with his two sons, G. W. and J. W., to the Southern army. He died in 1863 from harsh treatment received in Northern prisons. His son, JOHN W., was killed at the age of twenty-one, in a fight at Glasgow, Mo., while with Price on his raid into the State in 1863. JOHN WILLIS and BERNARD S. MCGUIRE died shortly after the war, and JAMES M. at his home in Jackson, Mo., in 1888.
Hunter Holmes McGuire

Hunter Holmes McGuire was a surgeon on the staffs of Stonewall Jackson, Richard Ewell, and Jubal Early in the American Civil War, or as Hunter would have insisted on calling it, "The War Between the States". Hunter was only twenty-five at the start of the Civil War. He was born on October 11, 1835, in Winchester, Virginia, in the Shenandoah Valley. Hunter was the fifth child of seven, and first son, in the family of eminent eye surgeon Dr. Hugh Holmes and Eliza McGuire's family. Hunter was a tall, thin, almost frail looking youth. He was respected as a studious loner by his peers for his courage, loyalty, and amiable disposition.

Hunter graduated from the Winchester Medical College in 1855. He enrolled the following year at the Thomas Jefferson Medical College in Philadelphia but was forced to return home due to an attack of acute rheumatism. Upon return home, young Dr. McGuire was named professor of anatomy at his alma mater in Winchester though he was just twenty-two. He soon returned to Philadelphia however to continue his studies. McGuire was highly thought of by associates in Pennsylvania including one, Dr. Lunkett who termed Hunter: "...overgrown youth is going to make a mark on the age".

He was still studying in Philadelphia at the time of John Brown's raid in 1859 on Harper's Ferry. With the growing resentment towards southerners in the city, McGuire led a group of southern medical students back to Virginia. In the sixteen months between leaving Philadelphia and the firing on Fort Sumter, McGuire moved to New Orleans where he taught medicine at Tulane University.

Hunter was a believer in the sovereignty of Virginia and the ideas of States Rights. His allegiance was to the state of Virginia; therefore, when Fort Sumter was fired upon, there was no question where McGuire would end up. He left New Orleans and joined The Winchester Rifles, company F of the 2nd Virginia Infantry as a private. McGuire did not remain a private for long. An administrator in Richmond found out who he was, and his services were much more valuable as a doctor rather than a front line soldier. McGuire was made a brigade surgeon and was ordered to report to General Thomas Jackson at Harper's Ferry. The dour Jackson was not impressed by his new medical director. McGuire was still recovering from an illness and looked frailer and even younger than his twenty-five years.

Jackson sent McGuire back to his quarters and wired Richmond to see if there was some mistake! McGuire and Jackson would soon become fast friends. McGuire would later comment that: The noblest heritage I shall hand down to my children is the fact that Stonewall Jackson condescended to hold me and to treat me as his friend.

Dr. McGuire, along with Stonewal Jackson, was at the first battle of Bull Run at Manassas when the Union and Confederate fought. Jackson was wounded in the middle finger of the hand. McGuire treated the finger by splinting and bandaging it. After Bull Run, McGuire spent the next three months near Centereville. In November, Jackson and his staff left for his new assignment in the Shenandoah Valley. Following the war Dr. McGuire returned to Winchester where he lived the rest of his life.

For more on Dr. Hunter Holmes McGuire I suggest the following web site by AP Hill.   http://members.aol.com/CWSurgeon0/hunter.html


1. Parish Records/Christ Church, Middlesex Co., VA
2.Crozier, VA County Records, Spotsylvania, p. 68.
4.Sparacia, Ruth & Sam DEEDS OF MIDDLESEX CO., VA
5.Marriage record/Clark Co., KY (Susan Daniel to Wm McGuire)
6.FGC from Bill Johnston
7.KY Historical Soc.
8.Iris Winkler/KY researcher
9.Mann, Robert & Catherine DANIEL FAMILY OF MIDDLESEX CO., VA
10. TYLER'S QUARTERLY Vol. 1 & 2 pp 111 -135.
11. LDS records
12. Virkus Vol 2
13. ESTILL CO., KY MARRIAGES by Edwards & Rose p.216, 217.
14. G. Payne Daniel, researcher.
15. Estill Co. Ky Rec. Vol 3 p.209;
16. Estill Co., KY Marriage Permissive Notes 1809-1892, Ed Puckett

1. The Will Of John McGuire, Clark County Ky.
2. Letter written in 1938 by O.R. McGuire of Arlington, VA, to Miss Ludie J. Kinkead, Curator of the Filson Club in Louisville, KY. I received a copy from Ruth Eager Moran.
3. Research done by Mr. James H. French of Winchester, Kentucky, and Mrs. A. E. Hart
4. Winchester-Frederick County Historical Society P.O. Box 58, Winchester, VA 22604
5. A Historical Guide Book to Winchester, Virginia, 1956, L. Adolph Richards of Winchester, VA,
6. Standard, William The McGuire Family in Virginia.
7. History of Southeast Missouri, page 780, Goodspeed, 1888
8. Deed book # 21 , page 431, Winchester Library, Winchester, Clark Co., KY

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