In April 1863, the regiment had a fight near Pikeville, Kentucky, and captured Colonel French and his command, and in June engaged the enemy again at Pond Creek, some thirty miles from Pikeville. The regiment being divided, a portion of it proceeded with other troops to Gladeville, Virginia, and succeeded in capturing Colonel Caudill and his command, who were brought back as prisoners of war.

Through the constant and vigilant service of this regiment, the east portion of Kentucky remained uninterrupted from any invasion of rebels for many months.

The regiment participated in many battles and skirmishes, in which loss was sustained, among which the following are mentioned, viz:

Johnson County boat fight, December 4th, 1862
Beaver Creek, Floyd County, June 27th, 1863
Clark's Neck, Lawrence County, August 27th, 1863
Marrowbone, Pike County, September 22nd, 1863
Paintsville, Johnson County, April 13th, 1864
Half Mount, Magoffin County, April 14th, 1864
Pond Creek, Pike County, May 16th, 1864
Mount Sterling, Kentucky, June 9th, 1864
Cynthiana, Kentucky, June 12th, 1864
Saltville, Virginia, October 2d, 1864

The regiment was mustered out September 15th, at Louisville, Kentucky.